More than two centuries ago, Native Americans discovered that the root of the black cohosh plant (Actaea racemosa, formerly known as Cimicifuga racemosa) helped relieve menstrual cramps and menopausal symptoms, such as hot flashes, irritability, mood swings, and sleep disturbances. Effects were assessed on physiological, molecular and biochemical level. Oscaby, F. [A chlorhexidine-rhubarb extract mixture for gingival inflammation]. 1993;13(5):286-8, 261-2. **This is a subjective assessment based on the strength of the available informations and our estimation of efficacy. Basu TK, Ooraikul B, and Garg M. The lipid-lowering effects of rhubarb stalk fiber: A new source of dietary fiber. They ask that you first approach the company that sold you the product for a refund. Taking rhubarb with other stimulant laxatives might cause more diarrhea and very low potassium levels. One customer reported of kidney failure after . It helps relieve night sweats and hot flushes while boosting your energy levels and improving sleep. Note that each number in parentheses [1, 2, 3, etc.] Federal government websites often end in .gov or .mil. The special extract ERr 731 from the roots of rhapontic rhubarb has been regularly prescribed for women with menopausal symptoms since 1993. This fools the body into thinking that theres enough estrogen available, stopping or decreasing the symptoms. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Unable to load your collection due to an error, Unable to load your delegates due to an error. They may work by disrupting cell membranes of bacteria and their protein and energy production. Your email address will not be published. Combined with dialysis, a Chinese medication with rhubarb (Xinqingning) reduced the buildup of toxins in the blood; it helped slow the progression of chronic kidney failure in 57 patients. Any use of this site constitutes your agreement to the Terms of Use and Privacy Policy mentioned here. Concern over the safety and effectiveness of hormone replacement therapy for relieving these symptoms has caused many women to seek alternative medical treatments. Kaszkin-Bettag M, Ventskovskiy BM, Kravchenko A, Rettenberger R, Richardson A, Heger PW, Heger M. The special extract ERr 731 of the roots of Rheum rhaponticum decreases anxiety and improves health state and general well-being in perimenopausal women. 1990;10(3):162-3, 133. Xu, F. and Fu, H. M. [Qing-shen tiao-zhi tablet in the treatment of hyperlipemia in the middle and old aged]. Characterization of the pharmacologic profile of a standardized soy extract in the ovariectomized rat model of menopause: effects on bone, uterus, and lipid profile. Zhang, Z. J., Cheng, W. W., and Yang, Y. M. [Low-dose of processed rhubarb in preventing pregnancy induced hypertension]. They can also kill cancer cells and prevent metastasis by blocking excessive cell division [8, 9]. Even though a greater number of treated children survived, death rates were still high (30%) [32]. Syrian rhubarb syrup (2.5 5 mL) along with an antibiotic (ceftriaxone) reduced fever, diarrhea, and the duration of stomach pain in a clinical trial of 150 children with an intestinal infection. Systematic review of published data on herb induced liver injury. Aleksa received his MS in Pharmacy from the University of Belgrade, his master thesis focusing on protein sources in plant-based diets. Mitsuma, T., Yokozawa, T., Oura, H., and Terasawa, K. [Rhubarb therapy in patients with chronic renal failure (Part 2)]. 2010 Feb;17(2):116-25. doi: 10.1016/j.phymed.2009.05.012. Gut bacteria then break them down into active metabolites, which reduce the amount of water the colon reabsorbs. Menopause. Long-term use can result in muscular weakness, bone loss, potassium loss, and irregular heart rhythm. Many people mentioned that it was a big disadvantage that the product had no black cohosh, as its meant to be an excellent remedy for hot flashes. No valid clinical evidence supports the use of rhubarb for any of the conditions in this section. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. Therapeutic Research Faculty 2020. Chinese rhubarb combined with mineral powder and blood purification was more effective at treating severe herbicide poisoning than the standard procedure. I suffered a small bout of kidney stones, which is rare. Nippon Jinzo Gakkai Shi 1993;35(1):13-18. On the other, there were also many negative reviews. How does alkaline phosphatase affect P-nitrophenol? Results of double-blind, randomised, controlled clinical trials]. Rodrguez-Archilla A, Raissouni T. Randomized clinical trial of the effectiveness of complementary therapies for recurrent aphthous stomatitis. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). 1997;36(2):87-89. Because rhubarb has a laxative effect, please discuss with your doctor before taking it with any medications. In conclusion, the observations from previous trials regarding the endometrial safety of ERr 731() have been supported by our experimental findings that exclude a stimulatory activity on proliferation in the uterus in a long-term administration in the young adult rat but no effect on the bone mineral density could be observed. 2016 Aug;46(8):677-82. ERr 731 also reduced anxiety from moderate-severe to slight, aside from reducing hot flashes in another clinical trial of 109 women transitioning to menopause [24]. Stimulant laxatives can cause diarrhea and decrease potassium levels. (Chinese Journal of Modern Developments in Traditional Medicine) 1984;4(2):88-89. All our customers, including ourselves, take Rhubarb Complex whilst working, socialising or travelling without any problems whatsoever. Zhong.Xi.Yi.Jie.He.Za Zhi. Li, L. S. and Liu, Z. H. [Clinical and experimental studies of rheum on preventing progression of chronic renal failure] (Chinese). Wilson M, Konda V, Heidt K, Rathinasabapathy T, Desai A, Komarnytsky S. Int J Mol Sci. It is possible that the supplement could contribute to the onset of night sweats within the first couple of months of use. Some women said it didnt work for them, and others said it brought on symptoms or even their period. Pregnancy can temporarily cause high blood pressure. Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. 2015 Mar;12(1):61-9. Hence, the modulation of proliferation in the uterus was investigated by examining the effects on the mRNA expression of proliferation marker genes (Mki67, Pcna), on the estrogen-responsive gene C3 and on the estrogen receptors ER and ER. Efficacy of Natural Formulation Containing Activated Charcoal, Calcium Sennosides, Peppermint Oil, Fennel Oil, Rhubarb Extract, and Purified Sulfur (Nucarb) in Relieving Constipation. A plus sign next to the number [1+, 2+, etc] means that the information is found within the full scientific study rather than the abstract. In addition, Estroven Complete provides other health benefits such as lessening stress levels and providing you with additional energy. Accessibility Rhubarb can cause some side effects such as stomach and intestinal pain, watery diarrhea, nausea, vomiting, rash, and uterine contractions. . In another trial of 89 critically-ill children, a Chinese herbal remedy (Fuan Liquid) added to conventional drugs successfully reduced gut dysfunction. Tenner S Baillie J, DeWitt J, Vege SS; American College of Gastroenterology. Careers. This supplement can soothe the joints and muscles. Postmenopause is the stage after menopause. It appears to have some benefits for the. Cisplatin (Platinol-AQ) interacts with BLACK COHOSH Cisplatin (Platinol-AQ) is used to treat cancer. Taking these products together might cause potassium levels to drop too low. You are covered by the return policy of the third-party website where you buy the product, however, this manufacturer also has a return policy. There were many good reviews from women who stated that this product had really changed their lives and made their period of menopause much easier. Speak with your doctor before supplementing. View abstract. Rhapontic rhubarb is used for many of the same reasons as black cohosh, and it's the active ingredient in the popular menopause supplement Estroven. Researchers found 12 weeks of treatment with a pill containing extract of Rheum rhaponticum, the vegetable more commonly known as rhubarb, significantly reduced the frequency and severity of hot. Rhapontic rhubarb is used for many of the same reasons as black cohosh, and it's the active ingredient in the popular . Liudvytska O, Ponczek MB, Ciesielski O, Krzyanowska-Kowalczyk J, Kowalczyk M, Balcerczyk A, Kolodziejczyk-Czepas J. Nutrients. Diarrhea can increase the effects of warfarin and increase the risk of bleeding. J Ethnopharmacol 2019;233:190-6. Rheum officinale (a traditional Chinese medicine) for chronic kidney disease. It was given alongside conventional treatment [11]. 1996;109(1):35-37. Zhongguo Zhong Xi Yi Jie He Za Zhi 1994;14(5):268-70, 259. View abstract. Med Clin (Barc). Sheng, Z. L., Li, N. Y., and Ge, X. P. [Clinical study of baoyuan dahuang decoction in the treatment of chronic renal failure]. The information contained in this website is provided for general informational purposes only. View abstract. Am J Chin Med 2005;33(6):839-850. Joe Cohen flipped the script on conventional and alternative medicine and it worked. Gallo D, Zannoni GF, Apollonio P, Martinelli E, Ferlini C, Passetti G, Riva A, Morazzoni P, Bombardelli E, Scambia G. Menopause. Rehman H, Begum W, Anjum F, Tabasum H, Zahid S. Effect of rhubarb (Rheum emodi) in primary dysmenorrhoea: a single-blind randomized controlled trial. - 1 tbsp flaxseed. Do not take black cohosh if you are taking cisplatin (Platinol-AQ). View abstract. Zhang, J. H., Li, L. S., and Zhang, M. Clinical effects of rheum and captopril on preventing progression of chronic renal failure. Hong Kong Med J 2006;12:394-7. Helps relieve 11 common & uncommon menopausal discomforts. A few small changes can go a long way toward increasing your pleasure during sex solo or partnered and boosting physical and emotional intimacy with your partner(s). If you take warfarin, do not take excessive amounts of rhubarb. Safety and efficacy of NT, an herbal supplement, in treating human obesity. Nusko G, Schneider B, Schneider I, et al. Mohtashami L, Amiri MS, Ayati Z, Ramezani M, Jamialahmadi T, Emami SA, Sahebkar A. Adv Exp Med Biol. What is Rhapontic Rhubarb root extract used for? Kang, Z., Bi, Z., Ji, W., Zhao, C., and Xie, Y. If youre not successful, you can request your money back from Estroven. Ali R, Irfan M, Akram U, et al. The full list of currently known side effects of black cohosh use includes: abnormal or increased vaginal discharge. The https:// ensures that you are connecting to the There is a report of kidney failure in someone who took a product containing rhubarb. Stimulant laxatives can cause diarrhea and decrease potassium levels. Most of rhubarbs oxalate is in its leaves, so trim them off and discard them, and youre safe. Estroven Complete is manufactured by i-Health, companies. All four analyses noted that the examined studies had poor methodological quality [28, 36, 47, 25]. Copyright 2011 Elsevier Ltd. All rights reserved. So, what side effects can Rhubarb cause? Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Estroven Complete can reduce the frequency of hot flashes by 80%. . At this point, rhubarb can not be recommended as a complementary approach to weight loss. How It Works Purported Uses and Benefits Do Not Take If Side Effects Special Point Back to top For Healthcare Professionals Scientific Name Clinical Summary Purported Uses and Benefits Mechanism of Action Adverse Reactions Herb-Drug Interactions References Back to top # A B C D E F G H I J K L Complement Ther Med. 1990;103(10):788-793. The extracts were effective against resistant strains, too [58]. Rhubarb is rich in antioxidants, particularly anthocyanins (which give it its red color) and proanthocyanidins. Am J Forensic Med Pathol. 1993;13(2):71-3, 67. Such symptoms include: hot flashes weight gain low metabolism mood shifts night sweats difficulty concentrating The. Li, L. Rheum officinale: a new lead in preventing progression of chronic renal failure. We believe that the most accurate information is found directly in the scientific source. Altern Ther Health Med. I have a brand new unopened box of it and if you would like it text me at 412 265-5865 or email me at